InstituteSafety & HealthGeneral Industry SafetyCompliance and Exceptions (Level 2)Toxic and Hazardous Substances - OSHACarcinogensEnglishAnalysisFocus AreaToxic and Hazardous Substances - OSHAUSA
13 carcinogens
['Toxic and Hazardous Substances - OSHA']

- The 13 carcinogens are a group of cancer-causing chemicals in the workplace that OSHA regulates.
- Protective measures against the 13 carcinogens include establishing regulated areas, providing employee PPE and decontamination areas, proper container labeling, and employee communication through a Hazard Communication Program.
The 13 carcinogens refer to a group of cancer-causing chemicals regulated by the Occupational Safety and Health Administration (OSHA). Employees who have contact with these chemicals must understand the hazards and the methods of control associated with these hazards.
The 13 carcinogens are:
- 4-Nitrobiphenyl
- alpha-Naphthylamine
- Methyl chloromethyl ether
- 3,3’-Dichlorobenzidine and its salts
- bis-Chloromethyl ether
- beta-Naphthylamine
- Benzidine
- 4-Aminodiphenyl
- Ethyleneimine
- beta-Propiolactone
- 2-Acetylaminofluorene
- 4-Dimethylaminoazo-benzene
- N-Nitrosodimethylamine
The requirements cover employers who have employees exposed to any of the 13 substances listed in the regulation, and to any area in which the 13 carcinogens are manufactured, processed, repackaged, released, handled, or stored. It does not apply to transshipment in sealed containers, except for certain labeling requirements specified in the regulation.
Employers must:
- Determine if any employees are exposed to any of the 13 carcinogens.
- Establish a regulated area if the 13 carcinogens are used.
- Allow only authorized employees to enter areas where substances are present.
- Ensure all employees who enter areas where substances are present are protected by PPE and other specified systems.
- Maintain procedures for decontamination after working in areas where the substances are present.
- Implement a respiratory protection program.
- Communicate hazards through a comprehensive Hazard Communication program.
- Ensure areas and containers are labeled properly.
- Implement a medical surveillance program.
- Maintain all employee exposure and medical records per 1910.1020.