InstituteSafety & HealthIn Depth Sub Topics (Level 4)General Industry SafetyToxic and Hazardous Substances - OSHACarcinogensEnglishAnalysisFocus AreaToxic and Hazardous Substances - OSHAUSA
Operations in hoods or closed systems
['Toxic and Hazardous Substances - OSHA']

- In operations where carcinogens are contained in a closed system, provisions such as restricted access, required PPE for workers, areas for removing contaminated clothing, and more are required.
In operations involving laboratory-type hoods, or in locations where the carcinogens are contained in an otherwise closed system, but is transferred, charged, or discharged into other normally closed containers, the following provisions apply:
- Access must be restricted to authorized employees only.
- Each operation must be provided with continuous local exhaust ventilation so that air movement is always from ordinary work areas to the operation. Exhaust air must not be discharged to regulated areas, nonregulated areas, or the external environment unless decontaminated. Clean makeup air must be introduced in sufficient volume to maintain the correct operation of the local exhaust system.
- Employees must be provided with, and required to wear, clean, full body protective clothing (smocks, coveralls, or long-sleeved shirt and pants), shoe covers and gloves prior to entering a regulated area.
- Employees engaged in handling operations involving the carcinogens must be provided with, and required to wear and use, a half-face, filter-type respirator for dusts, mists, and fumes, in accordance with 1910.134. A respirator affording higher levels of protection may be substituted.
- Prior to each exit from a regulated area, employees must be required to remove and leave protective clothing and equipment at the point of exit and at the last exit of the day, to place used clothing and equipment in impervious containers at the point of exit for purposes of decontamination or disposal. The contents of such impervious containers must be identified as required by the regulation.
- Drinking fountains are prohibited in the regulated area.
- Employees must be required to wash hands, forearms, face, and neck on each exit from the regulated area, close to the point of exit, and before engaging in other activities. Employees exposed to 4-Nitrobiphenyl; alpha-Naphthylamine; 3,3i-Dichlorobenzidine (and its salts); beta-Naphthylamine; Benzidine; 4-Aminodiphenyl; 2-Acetylaminofluorene; 4-Dimethylaminoazo-benzene; and N-Nitrosodimethylamine must be required to shower after the last exit of the day.