['Dangerous goods']
['Classification - Dangerous Goods']
07/17/2024
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2.35 (1) A mixture of liquids with an inhalation toxicity and an unknown LC50 is included in Packing Group I if it meets the following criteria:
(a) when a sample of the mixture is vapourized and diluted with air to create a test atmosphere of 1,000 mL/m3 and 10 young adult albino rats (5 male and 5 female) are exposed to the test atmosphere for 1 hour and observed for 14 days, the result is the death of 5 or more of the animals within the 14-day observation period; and
(b) when a sample of the vapour in equilibrium with the mixture at 20°C is diluted with 9 equal volumes of air to form a test atmosphere and 10 young adult albino rats (5 male and 5 female) are exposed to the test atmosphere for 1 hour and observed for 14 days, the result is the death of 5 or more of the animals within the 14-day observation period.
(2) A mixture of liquids with an inhalation toxicity and an unknown LC50 is included in Packing Group II if it meets the following criteria and the criteria for inclusion in Packing Group I are not met:
(a) when a sample of the mixture is vapourized and diluted with air to create a test atmosphere of 3,000 mL/m3 and 10 young adult albino rats (5 male and 5 female) are exposed to the test atmosphere for 1 hour and observed for 14 days, the result is the death of 5 or more of the animals within the 14-day observation period; and
(b) when a sample of the vapour in equilibrium with the mixture at 20°C is used to form a test atmosphere and 10 young adult albino rats (5 male and 5 female) are exposed to the test atmosphere for 1 hour and observed for 14 days, the result is the death of 5 or more of the animals within the 14-day observation period.
(3) A mixture of liquids with an inhalation toxicity and an unknown LC50 is included in Packing Group III if it meets the following criteria and the criteria for inclusion in Packing Group I or II are not met:
(a) when a sample of the mixture is vapourized and diluted with air to create a test atmosphere of 5,000 mL/m3 and 10 young adult albino rats (5 male and 5 female) are exposed to the test atmosphere for 1 hour and observed for 14 days, the result is the death of 5 or more of the animals within the 14-day observation period; and
(b) when the vapour pressure of the mixture is measured, the vapour concentration is greater than or equal to 1,000 mL/m3.
(4) If only LC50 data relating to 4-hour exposures to dust or mist are available, those figures can be multiplied by 4 and the result taken as the LC50 data for 1 hour, that is LC50 4 hours (dust or mist) multiplied by 4 is equivalent to LC50 1 hour.
(5) If only LC50 data relating to 4-hour exposures to vapour are available, those figures can be multiplied by 2 and the result taken as the LC50 data for 1 hour, that is LC50 4 hours (vapour) multiplied by 2 is equivalent to LC50 1 hour.
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['Dangerous goods']
['Classification - Dangerous Goods']
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