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§1308.14 Schedule IV.

RegSenseDrug and Alcohol TestingDrug and Alcohol TestingCFR RegulationsSubstance AbuseHR GeneralistCFR SectionUSAHR ManagementEnglishFocus AreaHuman Resources

Schedules of controlled substances

(a) Schedule IV shall consist of the drugs and other substances, by whatever official name, common or usual name, chemical name, or brand name designated, listed in this section. Each drug or substance has been assigned the DEA Controlled Substances Code Number set forth opposite it.

(b) Narcotic drugs. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation containing any of the following narcotic drugs, or their salts calculated as the free anhydrous base or alkaloid, in limited quantities as set forth below:

(1)Not more than 1 milligram of difenoxin and not less than 25 micrograms of atropine sulfate per dosage unit9167
(2)Dextropopoxyphene (alpha-(+)-4-dimethylamino-1,2-diphenyl-3-methyl-2-propionoxybutane)9278
(3)2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol, its salts, optical and geometric isomers and salts of these isomers (including tramadol)9752

(c) Depressants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances, including its salts, isomers, and salts of isomers whenever the existence of such salts, isomers, and salts of isomers is possible within the specific chemical designation:

(1)Alfaxalone2731
(2)Alprazolam2882
(3)Barbital2145
(4)Brexanolone2400
(5)Bromazepam2748
(6)Camazepam2749
(7)Carisoprodol8192
(8)Chloral betaine2460
(9)Chloral hydrate2465
(10)Chlordiazepoxide2744
(11)Clobazam2751
(12)Clonazepam2737
(13)Clorazepate2768
(14)Clotiazepam2752
(15)Cloxazolam2753
(16)Daridorexant2410
(17)Delorazepam2754
(18)Diazepam2765
(19)Dichloralphenazone2467
(20)Estazolam2756
(21)Ethchlorvynol2540
(22)Ethinamate2545
(23)Ethyl loflazepate2758
(24)Fludiazepam2759
(25)Flunitrazepam2763
(25)Flurazepam2767
(27)Fospropofol2138
(28)Halazepam2762
(29)Haloxazolam2771
(30)Ketazolam2772
(31) Lemborexant 2245
(32)Loprazolam2773
(33)Lorazepam2885
(34)Lormetazepam2774
(35)Mebutamate2800
(36)Medazepam2836
(37)Meprobamate2820
(38)Methohexital2264
(39)Methylphenobarbital (mephobarbital)2250
(40)Midazolam2884
(41)Nimetazepam2837
(42)Nitrazepam2834
(43)Nordiazepam2838
(44)Oxazepam2835
(45)Oxazolam2839
(46)Paraldehyde2585
(47)Petrichloral2591
(48)Phenobarbital2285
(49)Pinazepam2883
(50)Prazepam2764
(51)Quazepam2881
(52)Remimazolam2846
(53)Suvorexant2223
(54)Temazepam2925
(55)Tetrazepam2886
(56)Triazolam2887
(57)Zaleplon2781
(58)Zolpidem2783
(59)Zopiclone2784
(60)Zuranolone2420

(d) [Reserved]

(e) Lorcaserin. Any material, compound, mixture, or preparation which contains any quantity of the following substances, including its salts, isomers, and salts of such isomers, whenever the existence of such salts, isomers, and salts of isomers is possible:

(1)Lorcaserin1625

(f) Stimulants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances having a stimulant effect on the central nervous system, including its salts, isomers and salts of isomers:

(1)Cathine ((+)-norpseudophedrine)1230
(2)Diethylpropion1610
(3)Fencamfamin1760
(4)Fenproporex1575
(5)Mazindol1605
(6)Mefenorex1580
(7)Modafinil1680
(8)Pemoline (including organometallic complexes and chelates thereof)1530
(9)Phentermine1640
(10)Pipradrol1750
(11) Serdexmethylphenidate1729
(12)Sibutramine1675
(13)Solriamfetol (2-amino-3-phenylpropyl car-bamate; benzenepropanol, betaamino-, carbamate (ester))1650
(14)SPA ((-)-1-dimethylamino-1,2-diphenylethane)1635

(g) Other substances. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture or preparation which contains any quantity of the following substances, including its salts:

(1)Pentazocine9709
(2)Butorphanol9720
(3)Eluxadoline (5-[[[(2S)-2-amino-3-[4-aminocarbonyl)-2,6- dimethylphenyl]-1-oxopropyl][(1S)-1-(4-phenyl-1H-imidazol-2- yl)ethyl]amino]methyl]-2-methoxybenzoic acid) (including its optical isomers) and its salts, isomers, and salts of isomers. 9725

[74 FR 51235, Oct. 6, 2009; 76 FR 77358, Dec. 12, 2011; 78 FR 26705, May 8, 2013; 79 FR 10989, Feb. 27, 2014; 79 FR 37629, July 2, 2014; 79 FR 51247, Aug. 28, 2014; 80 FR 69864, Nov. 12, 2015; 84 FR 27943, June 17, 2019; 84 FR 27947, June 17, 2019; 85 FR 19391, April 7, 2020; 85 FR 63019, Oct. 6, 2020; 86 FR 24492, May 7, 2021; 87 FR 20317, Apr. 7, 2022; 87 FR 78859, Dec. 23, 2022; 88 FR 74352, Oct. 31, 2023]

['Drug and Alcohol Testing']
['Drug and Alcohol Testing', 'Substance Abuse']
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