May a driver with more than one normal work-reporting location use the 16-hour exception?

Yes. As stated in the 16-hour short-haul exception provision (395.1(o)) and the current Interpretation Question 15 to 395.1, a driver having more than one “normal” work-reporting location could use the 16-hour exception; however, its availability would be limited by the requirement of 395.1(o)(1) that the “carrier released the driver from duty at that location for the previous five duty tours the driver has worked ….” Assuming the driver’s normal duty tour is on a daily cycle, a driver alternating between two normal work locations on a weekly basis would not be able to use the exception unless the driver worked six days per week, and then the exception could only be used on the sixth day.