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Ethylene oxide (EtO) is produced in large volumes and is primarily used as an intermediate in the production of several industrial chemicals, the most notable of which is ethylene glycol. It is also used as a fumigant in certain agricultural products and as a sterilant for medical equipment and supplies. Unfortunately, EtO possesses several physical and health hazards that merit special attention. EtO is both flammable and highly reactive. Acute exposures to EtO gas may result in respiratory irritation and lung injury, headache, nausea, vomiting, diarrhea, shortness of breath, and cyanosis. Chronic exposure has been associated with the occurrence of cancer, reproductive effects, mutagenic changes, neurotoxicity, and sensitization.
OSHA’s EtO requirement applies to all occupational exposures EXCEPT the following:
If employee exposures exceed either the PEL or the excursion limit, employers must take the following actions: